Associations of Age and Sex With Marfan Phenotype: The National Heart, Lung, and Blood Institute GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) Registry [Original Articles]

Conclusions—
Pulmonary, skeletal, and aortic complications, but not other phenotypic features, are more prevalent in adults than children in Marfan syndrome. Aortic aneurysms and prophylactic aortic surgery are more common in men. Aortic dissection, commonly type B, occurs in an appreciable proportion of Marfan patients, especially in men and after previous prophylactic aortic root replacement.

Source: Circulation: Cardiovascular Genetics - June 9, 2017 Category: Cardiology Authors: Roman, M. J., Devereux, R. B., Preiss, L. R., Asch, F. M., Eagle, K. A., Holmes, K. W., LeMaire, S. A., Maslen, C. L., Milewicz, D. M., Morris, S. A., Prakash, S. K., Pyeritz, R. E., Ravekes, W. J., Shohet, R. V., Song, H. K., Weinsaft, J. W., for the Gen Tags: Genetics, Aneurysm, Aortic Dissection Original Articles Source Type: research