Effects of liver depression and psychological stress on human uterine leiomyoma cells by an AR –cAMP–PKA signal transduction pathway
Based on the emotional theory of Traditional Chinese Medicine, and combined with the modern medicine theory of psychological stress, a research model of human uterine leiomyoma cells (ULM) was cultured in vitro to determine the effectiveness of adrenergic receptor (AR) agonists in human ULM cell growth. In addition, we studied the functional influence of “liver depression and psychological stress theory” on fibroid formation by intervening in the AR–cAMP–PKA signaling pathway. The intention was to establish a new method to prevent and cure fibroids through “liver depression and psychological stress theory” and provide an experimental basis for the Traditional Chinese Medicine emotional theory.
Source: Taiwanese Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tian Xia, Shuang Li, Ruihong Ma, Sufen Guan, Jiacui Li, Hongqin Li, Hexin Zhang, Qiu Lin, Zhimei Zhao, Baojuan Wang Tags: Original Article Source Type: research