Effects of camptothecin derivatives and topoisomerase dual inhibitors on Trypanosoma cruzi growth and ultrastructure
Conclusions:
Taken together, our data showed that camptothecin is more efficient than its derivatives in decreasing T. cruzi proliferation. Furthermore, we conclude that drugs pertaining to a certain class of topoisomerase inhibitors may present different efficiencies as chemotherapeutical agents.
Source: Journal of Negative Results in BioMedicine - Category: Research Authors: Otto LacombeAline ZumaCamila da SilvaWanderley de SouzaMaria Motta Source Type: research
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