Constitutive and acquired mechanisms of resistance to immune checkpoint blockade in human cancer

A great advantage in harnessing the immune system against cancer is endowed in the peculiar characteristics of tumor-specific T lymphocytes, the ultimate effector mechanism: once activated, T cells patrol any tissue in our body in search of specific target cells. Thus, if well equipped and tightly controlled, tumor-specific T cells find and terminate only cancer cells [1].
Source: Cytokine and Growth Factor Reviews - Category: Molecular Biology Authors: Tags: Short survey Source Type: research