Pharmacokinetics and pharmacodynamics of propofol: changes in patients with frontal brain tumours

Conclusions: Brain tumours might alter the pharmacokinetics of propofol. Caution should be exerted when using propofol TCI in patients with frontal brain tumours due to higher clearance.Trial registry number: NCT01060631.
Source: British Journal of Anaesthesia - Category: Anesthesiology Source Type: research