Intrathecal IgM index correlates with a severe disease course in multiple sclerosis: Clinical and MRI results

Multiple sclerosis (MS) is a chronic autoimmune disease that progresses with axonal losses and demyelination of the central nervous system. The most important tool in the diagnosis of MS is magnetic resonance imaging (MRI), although cerebrospinal fluid (CSF) also provides valuable information. Although CSF findings can provide information about the course of MS as well as assisting with diagnosis, their specificity is limited, despite being an individual marker in several neurological diseases [1].
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research