Tomato (Lycopersicon esculentum) or Lycopene Supplementation Attenuates Ventricular Remodeling After Myocardial Infarction Through Different Mechanistic Pathways

The objective of this study was to evaluate the influence of tomato or lycopene supplementation on cardiac remodeling after myocardial infarction (MI). Male Wistar rats were assigned to four groups: the sham group (animals that underwent simulated surgery) that received a standard chow (S;n=18); the infarcted group that received a standard chow (MI;n=13); the infarcted group supplemented with lycopene (1 mg of lycopene/kg body weight/day), (MIL;n=16); and the infarcted group supplemented with tomato, (MIT;n=16).

Source: The Journal of Nutritional Biochemistry - June 1, 2017 Category: Biochemistry Authors: Bruna LB Pereira, Patr ícia P Reis, Fábio E Severino, Tainara P Felix, Mariana G Braz, Flávia R Nogueira, Renata A C Silva, Ana C Cardoso, Maria AM Lourenço, Amanda M Figueiredo, Fernanda Chiuso-Minicucci, Paula S Azevedo, Bertha F Polegato, Katashi O Source Type: research