Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population

Conclusions:
Using the CC mouse population model, we have demonstrated a complex and highly variable relationship between PERC and TCA toxicokinetics and toxicodynamics at the population level. https://doi.org/10.1289/EHP788

Received: 11 July 2016
Revised: 26 September 2016
Accepted: 25 October 2016
Published: 30 May 2017
Address correspondence to I. Rusyn, TAMU, Texas A&M University, College Station, TX 77843, USA. Telephone: [phone]. E-mail: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP788).
The authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - May 30, 2017 Category: Environmental Health Authors: Terrie Young Tags: Research Source Type: research