Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium

Conclusions: Functional and correlative studies are now needed to elucidate the potential links between germline genotype, epigenetic function, and cancer etiology. Impact: This approach provides novel insight into possible pleiotropic effects of genes involved in epigenetic processes. Cancer Epidemiol Biomarkers Prev; 26(6); 816–25. ©2017 AACR.

http://cebp.aacrjournals.org/cgi/content/short/26/6/816?rss=1

Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Toth, R., Scherer, D., Kelemen, L. E., Risch, A., Hazra, A., Balavarca, Y., Issa, J.-P. J., Moreno, V., Eeles, R. A., Ogino, S., Wu, X., Ye, Y., Hung, R. J., Goode, E. L., Ulrich, C. M., on behalf of the OCAC, CORECT, TRICL, ELLIPSE, DRIVE, and GAME-ON co Tags: Research Articles Source Type: research