Soy compared with milk protein in a Western diet changes fecal microbiota and decreases hepatic steatosis in obese OLETF rats

Soy protein is effective at preventing hepatic steatosis; however, the mechanisms are poorly understood. We tested the hypothesis that soy versus dairy protein-based diet would alter microbiota and attenuate hepatic steatosis in hyperphagic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Male OLETF rats were randomized to “Western” diets containing milk protein isolate (MPI), soy protein isolate (SPI), or 50:50 MPI/SPI (MS) (n=9–10/group; 21% kcal protein) for 16 weeks. SPI attenuated (P

Source: The Journal of Nutritional Biochemistry - May 31, 2017 Category: Biochemistry Authors: Matthew R. Panasevich, Colin M. Schuster, Kathryn E. Phillips, Grace M. Meers, Sree V. Chintapalli, Umesh D. Wankhade, Kartik Shankar, Dustie N. Butteiger, Elaine S. Krul, John P. Thyfault, R. Scott Rector Source Type: research