Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction [Coronary Heart Disease]

BackgroundPlaque erosion causes 30% of ST‐segment elevation myocardial infarctions, but the underlying cause is unknown. Inflammatory infiltrates are less abundant in erosion compared with rupture in autopsy studies. We hypothesized that erosion and rupture are associated with significant differences in intracoronary cytokines in vivo.Methods and ResultsForty ST‐segment elevation myocardial infarction patients with

Source: JAHA:Journal of the American Heart Association - May 3, 2017 Category: Cardiology Authors: Chandran, S., Watkins, J., Abdul-Aziz, A., Shafat, M., Calvert, P. A., Bowles, K. M., Flather, M. D., Rushworth, S. A., Ryding, A. D. Tags: Biomarkers, Inflammation, Myocardial Infarction, Optical Coherence Tomography (OCT), Percutaneous Coronary Intervention Original Research Source Type: research