Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats [Imaging]

ConclusionsNTN‐1 treatment preserved BBB integrity and improved neurological functions through a Deleted in Colorectal Cancer/focal adhesion kinase/RhoA signaling pathway after SAH. Thus, NTN‐1 may serve as a promising treatment to alleviate early brain injury following SAH.

Source: JAHA:Journal of the American Heart Association - May 19, 2017 Category: Cardiology Authors: Xie, Z., Enkhjargal, B., Reis, C., Huang, L., Wan, W., Tang, J., Cheng, Y., Zhang, J. H. Tags: Animal Models of Human Disease, Basic Science Research, Ischemia Original Research Source Type: research