Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress [Heart Failure]
ConclusionsHalofuginone activated the AAR pathway in the heart and attenuated the structural and functional effects of cardiac stress.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Qin, P., Arabacilar, P., Bernard, R. E., Bao, W., Olzinski, A. R., Guo, Y., Lal, H., Eisennagel, S. H., Platchek, M. C., Xie, W., del Rosario, J., Nayal, M., Lu, Q., Roethke, T., Schnackenberg, C. G., Wright, F., Quaile, M. P., Halsey, W. S., Hughes, A. M Tags: Fibrosis, Heart Failure, Hypertrophy Original Research Source Type: research