Reducing interferon'ce in stem cells

Nature Cell Biology 19, 597 (2017). doi:10.1038/ncb3544 Authors: Alycia Gardner & Brian Ruffell Little is known regarding how the interactions of stem cells with the immune system regulate their plasticity. A study now describes a mechanism by which normal breast and cancer stem cells utilize miR-199a to downregulate the corepressor LCOR and minimize responses to type I interferon.
Source: Nature Cell Biology - Category: Cytology Authors: Tags: News and Views Source Type: research