Reducing interferon'ce in stem cells
Nature Cell Biology 19, 597 (2017).
doi:10.1038/ncb3544
Authors: Alycia Gardner & Brian Ruffell
Little is known regarding how the interactions of stem cells with the immune system regulate their plasticity. A study now describes a mechanism by which normal breast and cancer stem cells utilize miR-199a to downregulate the corepressor LCOR and minimize responses to type I interferon.
Source: Nature Cell Biology - Category: Cytology Authors: Alycia Gardner Brian Ruffell Tags: News and Views Source Type: research