Cystic fibrosis: Thymosin α 1 rescues CFTR activity

Nature Reviews Drug Discovery 16, 386 (2017). doi:10.1038/nrd.2017.99 Author: Sarah Crunkhorn Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein and is characterized by chronic lung inflammation. Romani et al. show that the naturally occurring polypeptide thymosin α1 — clinically used as an immunotherapeutic agent —
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research