Neurological disorders: DAMPening damage after stroke
Nature Reviews Drug Discovery 16, 385 (2017).
doi:10.1038/nrd.2017.101
Author: Megan Cully
Much of the tissue injury that occurs following ischaemic stroke is caused by sterile inflammation, which lasts for about a week after the initial artery blockade. Shichita and colleagues have found that increasing transcription of macrophage scavenger receptor 1 (Msr1) reduced neurological deficits
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Megan Cully Tags: Research Highlight Source Type: research