Neurodegenerative disorders: Ataxin 2 reduction rescues motor defects

Nature Reviews Drug Discovery 16, 384 (2017). doi:10.1038/nrd.2017.104 Author: Sarah Crunkhorn Mutations in ATXN2, the gene encoding ataxin 2 — an RNA-binding protein found throughout the body with multiple roles in RNA metabolism — have been implicated in both amyotrophic lateral sclerosis (ALS) and spinocerebellar ataxia type 2 (SCA2). Writing in Nature, two new
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research