Genotoxicity testing approaches for the safety assessment of substances used in food contact materials prior to their authorization in the European Union

In this study, we provide an analysis of the data on genotoxicity testing gathered by EFSA on food contact materials for the period 1992–2015. We also illustrate practical examples of the approaches that EFSA took when evaluating “non standard” food contact chemicals (e.g., polymeric additives, oligomer or other reaction mixtures, and nanosubstances). Additionally, EFSA's experience gained from using non testing methods and/or future possibilities in this area are discussed. Environ. Mol. Mutagen., 2017. © 2017 Wiley Periodicals, Inc.

Source: Environmental and Molecular Mutagenesis - May 28, 2017 Category: Molecular Biology Authors: Claudia Bolognesi, Anna F. Castoldi, Riccardo Crebelli, Eric Barth élémy, Daniela Maurici, Detlef Wölfle, Katharina Volk, Laurence Castle Tags: Review Source Type: research