A Role for Primary Cilia in Aortic Valve Development and Disease

Conclusions: Our data support cilia as a novel cellular mechanism for restraining ECM production during aortic valve development and broadly implicate these structures in the etiology of BAV disease in humans. This article is protected by copyright. All rights reserved.

Source: Developmental Dynamics - May 27, 2017 Category: Molecular Biology Authors: Katelynn A Toomer, Diana Fulmer, Lilong Guo, Alex Drohan, Neal Peterson, Paige Swanson, Brittany Brooks, Rupak Mukherjee, Simon Body, Josh Lipschutz, Andy Wessels, Russell A. Norris Tags: Patterns & Phenotypes Source Type: research