Amphotericin Toxicity

A 42-year-old woman who had undergone left pneumonectomy for aspergilloma was discharged with oral posaconazole for residual fungal disease. She later presented to the outpatient infectious disease (ID) clinic after two weeks of pain, erythema, and purulent drainage around her sternotomy site. She was diagnosed with sternal osteomyelitis with multiple areas of fluid collection, which was thought to be a result of contiguous spread of aspergilloma. After surgical debridement, tissue cultures revealed Aspergillus fumigatus.
Source: AORN Journal - Category: Nursing Tags: Column Source Type: research