Adenine N6-methylation in diverse fungi
Nature Genetics 49, 823 (2017).
doi:10.1038/ng.3873
Author: Michael F Seidl
A DNA modification—methylation of cytosines and adenines—has important roles in diverse processes such as regulation of gene expression and genome stability, yet until recently adenine methylation had been considered to be only a hallmark of prokaryotes. A new study identifies abundant adenine methylation of transcriptionally active genes in early-diverging fungi that, together with recent other work, emphasizes the importance of adenine methylation in eukaryotes.
Source: Nature Genetics - Category: Genetics & Stem Cells Authors: Michael F Seidl Tags: News and Views Source Type: research