Antigen-inexperienced memory CD8+ T cells: where they come from and why we need them

Nature Reviews Immunology 17, 391 (2017). doi:10.1038/nri.2017.34 Authors: Jason T. White, Eric W. Cross & Ross M. Kedl Memory-phenotype CD8+ T cells exist in substantial numbers within hosts that have not been exposed to either foreign antigen or overt lymphopenia. These antigen-inexperienced memory-phenotype T cells can be divided into two major subsets: 'innate memory' T cells and 'virtual memory' T cells.
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Perspectives Source Type: research