The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice
In conclusion, prolame administration promotes hippocampal plasticity processes but not in the NAcc neurons of aged mice, thus improving long‐term recognition memory. Prolame could become a pharmacological alternative to prevent or delay the brain aging process, and thus the emergence of neurodegenerative diseases that affect memory. This article is protected by copyright. All rights reserved.
The treatment with prolame improves the recognition memory and dendritic morphology of the hippocampus and NAcc in aging mice, providing more evidence to be considered as a tool to delay the aging of the brain.
Source: Synapse - Category: Neurology Authors: Alfonso Diaz, Samuel Trevi ño, Rubén Vázquez‐Roque, Berenice Venegas, Blanca Espinosa, Gonzalo Flores, Juan Manuel Fernández‐G, Luis F. Montaño, Jorge Guevara Tags: Research Article Source Type: research