Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem

The carbapenem subclass of β-lactams is among the most potent antibiotics available today. Emerging evidence shows that, unlike other subclasses of β-lactams, carbapenems bind to and inhibit non-classical tran...

Source: BMC Biochemistry - May 25, 2017 Category: Biochemistry Authors: Mario A. Bianchet, Ying H. Pan, Leighanne A. Brammer Basta, Harry Saavedra, Evan P. Lloyd, Pankaj Kumar, Rohini Mattoo, Craig A. Townsend and Gyanu Lamichhane Source Type: research