A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017)

We report an additional case of POT in the maxilla of an 8‐year‐old girl presenting with an asymptomatic buccal enlargement. A well‐defined, unilocular, radiolucent lesion was observed radiographically. Histologically, the tumor was mostly composed of loose fibrous connective tissue resembling dental papilla and a single layer of columnar epithelium covering the periphery of the tumor. In part, cords or nests of epithelium were present in the mesenchyme close to the periphery. Nestin, a marker of odontogenic ectomesenchyme, was positive in the mesenchymal tumor cells. We finally diagnosed the lesion as POT considering the possibility of other odontogenic tumors like ameloblastic fibroma or developing odontoma as a differential diagnosis. The patient shows no recurrence after 16 months. This case is the first report from Japan using this novel diagnosis POT after it was recognized and defined in the latest WHO classification.
Source: Pathology International - Category: Pathology Authors: Tags: Case Report Source Type: research