Treatment of Acute Pouchitis

Acute pouchitis is a common disease that affects many patients with an ileal pouch-anal anastomosis. The management of acute pouchitis remains largely empiric with the mainstay of therapy being the antibiotics ciprofloxacin and metronidazole. Probiotics may have a role in the primary and secondary prophylaxis of acute pouchitis. In addition, there is modest data that probiotics are effective in the treatment of mild acute pouchitis. There is limited data for other treatments of acute pouchitis including oral and rectal budesonide and butyrate enemas.
Source: Seminars in Colon and Rectal Surgery - Category: Gastroenterology Authors: Source Type: research