Ageing is associated with brown adipose tissue remodelling and loss of white fat browning in female C57BL/6 mice

In conclusion, our results indicate that female C57BL/6 mice have a progressive age‐dependent loss of subcutaneous and visceral WAT browning, and this process runs in parallel with BAT morphological changes towards a fat storer phenotype, independent of cycling or disturbances in glucose metabolism.

Source: International Journal of Experimental Pathology - December 1, 2016 Category: Pathology Authors: Leidyanne Ferreira Gon çalves, Thaissa Queiroz Machado, Camila Castro‐Pinheiro, Nathalia Guimaraes Souza, Karen Jesus Oliveira, Caroline Fernandes‐Santos Tags: Original Article Source Type: research