Planar cell polarity in development and disease

Nature Reviews Molecular Cell Biology 18, 375 (2017). doi:10.1038/nrm.2017.11 Authors: Mitchell T. Butler & John B. Wallingford Planar cell polarity (PCP) is an essential feature of animal tissues, whereby distinct polarity is established within the plane of a cell sheet. Tissue-wide establishment of PCP is driven by multiple global cues, including gradients of gene expression, gradients of secreted WNT ligands and anisotropic
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research