The HSP90 chaperone machinery
Nature Reviews Molecular Cell Biology 18, 345 (2017).
doi:10.1038/nrm.2017.20
Authors: Florian H. Schopf, Maximilian M. Biebl & Johannes Buchner
The heat shock protein 90 (HSP90) chaperone machinery is a key regulator of proteostasis under both physiological and stress conditions in eukaryotic cells. As HSP90 has several hundred protein substrates (or 'clients'), it is involved in many cellular processes beyond protein folding, which include DNA
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Florian H. Schopf Maximilian M. Biebl Johannes Buchner Tags: Review Source Type: research