Charting the unknown epitranscriptome

Nature Reviews Molecular Cell Biology 18, 339 (2017). doi:10.1038/nrm.2017.49 Authors: Eva Maria Novoa, Christopher E. Mason & John S. Mattick RNA modifications can alter RNA structure–function relationships and various cellular processes. However, the genomic distribution and biological roles of most RNA modifications remain uncharacterized. Here, we propose using phage display antibody technology and direct sequencing through nanopores to facilitate systematic interrogation of the distribution, location
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Comment Source Type: research