A patient with autoimmune limb-girdle myasthenia, and a brief review of this treatable condition.

Limb-girdle myasthenia gravis (LGM) is an uncommon clinical picture with a peculiar proximal distribution of the muscle weakness with no ocular, bulbar or facial deficit. This condition could mimic some myopathies or be caused by congenital defects of the neuromuscular transmission. However such an onset is more frequent during infancy then in adulthood. The diagnosis of myasthenia could be suggested by: the decremental responses to repetitive nerve stimulation (RNS), the thymus pathology, or the evidence, despite rarely found, of anti-acetylcholine receptor antibodies (AchRAbs) [1].
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Tags: Review Source Type: research