Urtica dioica for treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia

This study was conducted to investigate the effect of Urtica dioica on the clinical symptoms of BPH. This double‐blind clinical trial included 248 patients with symptomatic BPH in Shohada Ashayer Hospital of Khorramabad. The patients were randomly divided into four groups of treatment with U. dioica 3 g, U. dioica 5 g, U. dioica 7 g and treatment with prazosin 1 mg alone as the control group. The clinical symptoms, patients' quality of life and level of serum prostate‐specific antigen (PSA) were measured before and 2 months after the intervention. The results of the study showed significant differences between the four groups after the intervention for the scores of clinical symptoms and patients' quality of life, while no significant differences were found for serum PSA levels. Sheffe post hoc comparisons showed significant improvements in the scores of the patients' clinical symptom in the U. dioica 5 g/d and U. dioica 7 g/d groups. The results of the study showed that simultaneous consumption of higher doses of U. dioica, up to 7 g/d, plus prazosin, compared with the consumption of prazosin alone, resulted in significant improvements in the clinical symptoms of BPH.

Source: International Journal of Urological Nursing - March 1, 2014 Category: Urology & Nephrology Authors: Reza Hosseinabadi, Mohammad Heidari, Khatereh Anbari, Yadollah Pournia Tags: Research Paper Source Type: research