MicroCT-based finite element models as a tool for virtual testing of cortical bone

Knowledge of the elastic, yield, and failure properties of trabecular and cortical bone tissue is very useful in investigating the skeletal effects of drug treatments, aging, and disease. Mechanical testing has been considered as a standard tool for investigating various effects on the extrinsic (stiffness, yield force etc.) and intrinsic (Young's modulus, yield stress etc.) properties of bone for decades [1]. However, recent advances in medical image resolution and computer processor speed provide alternatives, reducing the need for invasive mechanical testing and replacing it with computational biomechanics to simulate in-vivo bone-loading conditions.
Source: Medical Engineering and Physics - Category: Biomedical Engineering Authors: Source Type: research