Intraventricular administration of Tenebrio molitor larvae extract regulates food intake and body weight in mice with high fat diet-induced obesity

We recently reported the in vitro and in vivo anti-obesity effects of Tenebrio molitor larvae, a traditional food in many countries, but it remains unknown how the larvae affect appetite regulation in mice with diet-induced obesity. We hypothesized that the extract of T. molitor larvae mediate appetite by regulating neuropeptide expression. We investigated T. molitor larvae extract's (TME's) effects on anorexigenesis and endoplasmic reticulum (ER) stress-induced orexigenic neuropeptide expression in the hypothalami of obese mice.
Source: Nutrition Research - Category: Nutrition Authors: Source Type: research