STAT5 alters the state of transcriptional networks, driving aggressive leukemia

Nature Immunology 18, 597 (2017). doi:10.1038/ni.3747 Authors: Sinisa Dovat & Kimberly J Payne The transcription factor STAT5 acts as an oncoprotein in B cell acute lymphoblastic leukemia, competing with the transcription factors NF-κB and Ikaros for binding to DNA.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Tags: News and Views Source Type: research