Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice

In conclusion, our data suggest that the function of SIRT6 in the Fabp4-Cre-expressing cells in addition to mature adipocytes plays a critical role in body weight maintenance and metabolic homeostasis.

Source: Journal of Endocrinology - May 18, 2017 Category: Endocrinology Authors: Xiong, X., Zhang, C., Zhang, Y., Fan, R., Qian, X., Dong, X. C. Tags: Research Source Type: research