Anticancer therapy: Re-educating macrophages

Nature Reviews Drug Discovery 16, 313 (2017). doi:10.1038/nrd.2017.82 Author: M. Teresa Villanueva Despite being the main effectors of the innate immune response and programmed to detect and eliminate mutated cells, macrophages can change their phenotype and become pro-tumorigenic in response to cues from the tumour. Given their position within the tumour mass, tumour-associated macrophages (TAMs) are an
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research