Anticancer therapy: Re-educating macrophages
Nature Reviews Drug Discovery 16, 313 (2017).
doi:10.1038/nrd.2017.82
Author: M. Teresa Villanueva
Despite being the main effectors of the innate immune response and programmed to detect and eliminate mutated cells, macrophages can change their phenotype and become pro-tumorigenic in response to cues from the tumour. Given their position within the tumour mass, tumour-associated macrophages (TAMs) are an
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: M. Teresa Villanueva Tags: Research Highlight Source Type: research
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