Metabolic Disease: Protein tyrosine phosphatase inhibitor reverses diabetes

Nature Reviews Drug Discovery 16, 312 (2017). doi:10.1038/nrd.2017.73 Author: Sarah Crunkhorn The development of oral insulin-sensitizing agents to minimize the need for injectable insulin remains a major unmet need in the treatment of diabetes. Now, writing in Nature Chemical Biology, Bottini and colleagues report the identification of the first orally available small-molecule inhibitor of the
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research