Metastasis: Breaching barriers
Nature Reviews Cancer 17, 270 (2017).
doi:10.1038/nrc.2017.27
Author: Anna Dart
Boire et al. describe a mechanism by which cancer cells can survive and grow in the leptomeninges of the brain by upregulating complement component 3 (C3) to disrupt blood–cerebrospinal fluid barrier function, allowing entry of growth-promoting factors.
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Anna Dart Tags: Research Highlight Source Type: research