Generation of diversity in thymic epithelial cells

Nature Reviews Immunology 17, 295 (2017). doi:10.1038/nri.2017.12 Authors: Yousuke Takahama, Izumi Ohigashi, Song Baik & Graham Anderson In the thymus, diverse populations of thymic epithelial cells (TECs), including cortical and medullary TECs and their subpopulations, have distinct roles in coordinating the development and repertoire selection of functionally competent and self-tolerant T cells. Here, we review the expanding diversity in TEC subpopulations in
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research