Regulatory feedback from nascent RNA to chromatin and transcription

Nature Reviews Molecular Cell Biology 18, 331 (2017). doi:10.1038/nrm.2017.12 Authors: Lenka Skalska, Manuel Beltran-Nebot, Jernej Ule & Richard G. Jenner Transcription and chromatin function are regulated by proteins that bind to DNA, nucleosomes or RNA polymerase II, with specific non-coding RNAs (ncRNAs) functioning to modulate their recruitment or activity. Unlike ncRNAs, nascent pre-mRNA was considered to be primarily a passive player in these processes. In
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Perspectives Source Type: research