Variants of core histones and their roles in cell fate decisions, development and cancer

Nature Reviews Molecular Cell Biology 18, 299 (2017). doi:10.1038/nrm.2016.166 Authors: Marcus Buschbeck & Sandra B. Hake Histone variants endow chromatin with unique properties and show a specific genomic distribution that is regulated by specific deposition and removal machineries. These variants — in particular, H2A.Z, macroH2A and H3.3 — have important roles in early embryonic development, and they regulate the lineage commitment
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research