The brain, sirtuins, and ageing
Nature Reviews Neuroscience 18, 362 (2017).
doi:10.1038/nrn.2017.42
Authors: Akiko Satoh, Shin-ichiro Imai & Leonard Guarente
In mammals, recent studies have demonstrated that the brain, the hypothalamus in particular, is a key bidirectional integrator of humoral and neural information from peripheral tissues, thus influencing ageing both in the brain and at the 'systemic' level. CNS decline drives the progressive impairment of
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Akiko Satoh Shin-ichiro Imai Leonard Guarente Tags: Review Source Type: research