Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

Eukaryotic tRNA splicing is an essential process in the transformation of a primary tRNA transcript into a mature functional tRNA molecule. 5 ′-phosphate ligation involves two steps: a healing reaction catalyze...

Source: BMC Biochemistry - May 16, 2017 Category: Biochemistry Authors: Gopinath Muruganandam, Arne Raasakka, Matti Myllykoski, Inari Kursula and Petri Kursula Source Type: research