Proteomic Analysis of Synovial Fluid Obtained from a Dog Diagnosed with Idiopathic Immune-Mediated Polyarthritis

This case study is to report the proteins detected by proteomic analysis of synovial fluid from a dog diagnosed with idiopathic immune-mediated polyarthritis (IMPA), and to compare it with healthy dogs. Synovial fluid was collected via arthrocentesis from a dog diagnosed with IMPA. Protein precipitation was performed on the synovial fluid, followed by isoelectric focusing and two-dimensional gel electrophoresis. The spots on the two-dimensional gels were analyzed using MALDI-TOF/MS. The results were then analyzed against the MASCOT database.
Source: Topics in Companion Animal Medicine - Category: Veterinary Research Authors: Source Type: research