Efficacy and safety of carbetocin given as an intravenous bolus compared with short infusion for Caesarean section - double-blind, double-dummy, randomized controlled non-inferiority trial

Conclusions. Administration of carbetocin as short infusion does not compromise uterine tone and has similar cardiovascular side-effects as a slow i.v. bolus. In accordance with current recommendations for oxytocin, carbetocin can safely be administered as short -infusion during planned or unplanned CS.Clinical trial registration. ClinicalTrials.gov NCT02221531 andwww.kofam.ch SNCTP000001197.
Source: British Journal of Anaesthesia - Category: Anesthesiology Source Type: research