Pharmacokinetic/pharmacodynamic model for unfractionated heparin dosing during cardiopulmonary bypass

Conclusions. A population PK/PD analysis of heparin during CPB, using a routine haemostatic test, shows that Bayesian estimation might help to predict ACT on the basis of only one or two blood samples.
Source: British Journal of Anaesthesia - Category: Anesthesiology Source Type: research