Bergmann glia translocation: a new disease marker for Vanishing White Matter identifies therapeutic effects of Guanabenz treatment

ConclusionsBergmann glia translocation can be used to objectively assess effects of treatment in VWM mice. Future treatment strategies involving compounds regulating eIF2 phosphorylation might benefit VWM patients.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - April 1, 2017 Category: Neurology Authors: Stephanie Dooves, Marianna Bugiani, Lisanne Wisse, Truus E.M. Abbink, Marjo S. van der Knaap, Vivi M. Heine Tags: Original Article Source Type: research