A CRISPR toolbox to study virus –host interactions

Nature Reviews Microbiology 15, 351 (2017).
doi:10.1038/nrmicro.2017.29

Authors: Andreas S. Puschnik, Karim Majzoub, Yaw Shin Ooi & Jan E. Carette
Viruses depend on their hosts to complete their replication cycles; they exploit cellular receptors for entry and hijack cellular functions to replicate their genome, assemble progeny virions and spread. Recently, genome-scale CRISPR–Cas screens have been used to identify host factors that are required for virus

Source: Nature Reviews Microbiology - April 19, 2017 Category: Microbiology Authors: Andreas S. Puschnik Karim Majzoub Yaw Shin Ooi Jan E. Carette Tags: Review Source Type: research