Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis

In conclusion, data revealed that the suppressive capacity of Treg on viral elimination is efficiently boosted by CD8‐depletion, which renders C57BL/6 mice susceptible to develop chronic neuroinfection and TMEV‐IDD.

Source: Brain Pathology - May 12, 2017 Category: Neurology Authors: Malgorzata Ciurkiewicz, Vanessa Herder, Muhammad Akram Khan, Ann ‐Kathrin Uhde, René Teich, Stephan Floess, Wolfgang Baumgärtner, Jochen Huehn, Andreas Beineke Tags: Research Article Source Type: research